Predefined Single-Use Production Platforms for Biomanufacturing
The biopharmaceutical industry can reduce the time and cost required to bring products to the clinic and the market by taking advantage of single-use production platforms. These platforms integrate proven services and technologies for the development and manufacture of mAbs, vaccines, and bioconjugates.
Companies can streamline early-stage process development activities by leveraging the expertise and experience Sartorius has acquired over many years while establishing biomanufacturing processes for clients. Furthermore, Sartorius can expedite the engineering of single-use and hybrid processes for scale-up during late-stage activities using process templates that reduce design costs and increase standardization.
mAbs - Monoclonal Antibodies
Scalable and Cost-Efficient Single-Use Toolbox for Your mAb Process Platform
By combining our expertise in cell line development and cultivation, media optimization, virus clearance, filtration and polishing of mAbs we provide a complete Toolbox of Solutions which can be adapted in-house or at contract manufacturing organizations.
Accelerate Upstream Development and Simplify Manufacturing
Proven Process Solutions from Cell Line, Media and Process Development to Commercial Manufacturing
Speed up your development with a fully scaleable range of cell line, media, process development and characterization tools. Simplify manufacturing with completely single use upstream processing concepts based on classic stirred tank bioreactors complemented with media preparation and storage solutions and completely novel, large scale clarification based on dynamic body feed.
High Throughput Process Development Tools Enabling Effective QbD Strategies
Automated multi-parallel mini bioreactors and classic benchtop bioreactors enhanced with modern sensor technology and chemometrics tools enable fast and reliable development and characterization of your processes. Seamless transfer to pilot and production scale is guaranteed by thorough understanding of bioreactor design and scale-up principles and bioprocess adapted data management and automation concepts.
Achieve High Recovery and Purity with a Simplified Downstream Process
Implement Unique Technologies for Your Bioprocess Platform
Our Process Development Team and Applications Specialists will show you all the options available for your Downstream mAb Process. The perfect mAb platform is flexible and can be quickly adapted to each new operating conditions. It can be scaled up from the purification of mg to kg of proteins, and easily transferred to various manufacturing plants. From primary recovery to polishing, including bioburden reduction, virus clearance strategy and buffer management; we offer cost-effective and robust single-use technologies as well as innovative solutions for an effective handling of your purified drug substance.
